30 January 2015
In a role reversal, RNAs proofread themselves
Molecular photographs of an enzyme bound to RNA reveal a new, inherent quality control mechanism.
29 January 2015
New protein detonates ‘invincible’ bacteria from within
Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of bacteria resistant to antibiotics knows no borders, present
28 January 2015
Respiratory chain: protein complex structure revealed
Biochemists have unlocked the structure of mitochondrial complex 1, a large protein complex in the respiratory chain, and at the same time learned new aspects of its function.
27 January 2015
How to unboil an egg
UC Irvine and Australian chemists have found out how to unboil egg whites – an innovation that could dramatically reduce costs for cancer treatments, food production and other parts of the biotechnology industry.
26 January 2015
Telomere extension turns back aging clock in cultured human cells
A new procedure can quickly and efficiently increase the length of human telomeres, the protective caps on the ends of chromosomes that are linked to aging and disease, according to scientists at the Stanford University School of Medicine.
23 January 2015
Genome-wide search reveals new genes involved in long-term memory
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging.
22 January 2015
Unexpected turn in diabetes research
Years of diabetes research carried out on mice whose DNA had been altered with a human growth hormone gene is now ripe for reinterpretation after a new study shows that the gene had an unintended effect on the mice’s insulin production.
21 January 2015
A chemical modified version of the second messenger cAMP
Second messengers are small molecules that transmit signals in the cell. A single second messenger typically interacts with several signalling proteins.
20 January 2015
Predatory sea snails produce weaponized insulin
Cone snails produce a vast array of fast-acting toxins that target the nervous systems of prey. A new study reveals that some cone snails add a weaponized form of insulin to the venom cocktail they use to disable fish.
19 January 2015
Damaged DNA amplified
In the majority of cases, the onset of cancer is characterized by a minor change in a person’s genetic material. A cell’s DNA mutates to the extent that the cell no longer divides in a controlled manner, but begins to grow uncontrollably.
16 January 2015
Study in C. elegans shows excess iron promotes aging
It’s been known for decades that some metals, including iron, accumulate in human tissues during aging and that toxic levels of iron have been linked to neurologic diseases, such as Parkinson’s.
15 January 2015
Coenzyme A plays leading role in nitric oxide function so essential to cell metabolism
Case Western Reserve and University Hospitals (UH) Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide.
14 January 2015
Study sheds light on chemicals that insects use to communicate and survive
Most insects are covered with a thin layer of hydrocarbon molecules as a waterproofing barrier. Embedded in this layer are compounds that the insects use as chemical signals for a wide variety of functions such as communicating species, caste and sex.
13 January 2015
The epigenetic switchboard
Epigenetic signals help determine which genes are activated and when. A new method enables systematic characterization of the relevant epigenetic tags, and reveals that the system adapts to the loss of single epigenetic writer and eraser enzymes.
12 January 2015
Solving a case of intercellular entrapment
Optogenetics, which uses light to control cellular events, is poised to become an important technology in molecular biology and beyond.