20 October 2014
New insight that ‘mega’ cells control the growth of blood-producing cells
While megakaryocytes are best known for producing platelets that heal wounds, these ‘mega’ cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research.
17 October 2014
How mitochondria began
Parasitic bacteria were the first cousins of the mitochondria that power cells in animals and plants – and first acted as energy parasites in those cells before becoming beneficial, according to a new University of Virginia study.
16 October 2014
Scientists map key moment in assembly of DNA-splitting molecular machine
New work has revealed the crucial steps and surprising structures in the genesis of the enzyme that divides the DNA double helix during cell replication.
15 October 2014
Prostate cancer’s penchant for copper may be a fatal flaw
Prostate cancer tumours scavenge and hoard copper that is an essential element in the body. But such avarice may be a fatal weakness.
14 October 2014
Moderate levels of ‘free radicals’ found beneficial to healing wounds
Long assumed to be destructive to tissues and cells, ‘free radicals’ generated by the cell’s mitochondria—the energy producing structures in the cell—are actually beneficial to healing wounds.
13 October 2014
Atomic map reveals clues to how cholesterol is made
In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell’s membrane, helping to shape the cell and protect it.
10 October 2014
Hormone loss could be involved in colon cancer
Some cancers, like breast and prostate cancer, are driven by hormones such as oestrogen and testosterone, but to date, there are none that are driven by the lack of a hormone.
9 October 2014
Conspicuous tRNA lookalikes riddle the human genome
Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly.
8 October 2014
A universal Ebola drug target
A new study reports the design and characterization of universally conserved drug target for current and future strains of Ebola.
7 October 2014
Cells on the fast track
During cancer metastasis, immune response cells are moving in a controlled manner through the body. Researchers from the University of Basel discovered novel mechanisms of cell migration by observing cells moving on lines of connective tissue.
6 October 2014
Scientists develop barcoding tool for stem cells
A 7-year-project to develop a barcoding and tracking system for tissue stem cells has revealed previously unrecognized features of normal blood production.
3 October 2014
Discovery helps to spot what makes a good drug
A new test developed by researchers from The University of Manchester could revolutionise the discovery of new prescription drugs.
2 October 2014
Research pinpoints microRNA tied to colon cancer tumour growth
Researchers at the University of Minnesota have identified microRNAs that may cause colon polyps from turning cancerous. The finding could help physicians provide more specialized, and earlier, treatment before colon cancer develops.
1 October 2014
Driving cancer cells to suicide
Researchers at Ludwig-Maximilians-Universität München (LMU) report that a new class of chemical compounds makes cancer cells more sensitive to chemotherapeutic drugs. They have also pinpointed the relevant target enzyme, identifying a new drug target.
30 September 2014
Characterization of a molecular mechanism involved in cellular proliferation
Scientists have uncovered the molecular interaction between TACC3 and chTOG, key proteins in forming the internal cellular framework that enables and sustains cell division.