1 August 2014
Strict genomic partitioning by biological clock separates key metabolic functions
Much of the liver’s metabolic function is governed by circadian rhythms – our own body clock – and UC Irvine researchers have now found two independent mechanisms by which this occurs.
31 July 2014
Engineering a protein to prevent brain damage from toxic agents
Research at New York University is paving the way for a breakthrough that may prevent brain damage in civilians and military troops exposed to poisonous chemicals – particularly those in pesticides and chemical weapons.
30 July 2014
Research may explain how foremost anticancer ‘guardian’ protein learnt to switch sides
Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new function of the body’s most important tumour-suppressing protein.
29 July 2014
New protein structure could help treat Alzheimer’s and related diseases
There is no cure for Alzheimer’s disease and other forms of dementia, but the research community is one step closer to finding treatment.
28 July 2014
Scientists discover new, noncommittal mechanism of drug resistance
Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs. These permanent mutations were once thought to be the only way for drug-resistant strains to evolve.
25 July 2014
Researchers identify a treatment that prevents tumour metastasis
Metastasis is the strategy adopted by tumour cells to transform into an aggressive form of cancer. Managing to block the metastasis or, even better, prevent their formation would be a giant step in the fight against cancer.
24 July 2014
How to drive DNA knots with an electric potential
DNA has the habit of getting tangled and forming knots. Scientists study these knots to understand their function and learn how to disentangle them (e.g. useful for gene sequencing techniques).
23 July 2014
A new cellular waste control pathway with relevance for human neurodegenerative diseases
Several human neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s disease but also ageing, are linked to an accumulation of abnormal and aggregated proteins in cells.
22 July 2014
Mycobacteria metabolism discovery may pave way for new TB drugs
The mystery of why mycobacteria – a family that includes the microbe that causes TB – are extraordinarily hardy organisms is being unravelled by research that offers new hope for developing a revolutionary class of antibiotics to tackle TB.
21 July 2014
Scientists map one of most important proteins in life – and cancer
Scientists reveal the structure of one of the most important and complicated proteins in cell division – a fundamental process in life and the development of cancer – in research published in Nature.
18 July 2014
Scientists shed new light on nerve cell growth
Amid the astounding complexity of the billions of nerve cells and trillions of synaptic connections in the brain, how do nerve cells decide how far to grow or how many connections to build? How do they co-ordinate these events within the developing brain?
17 July 2014
Scientists develop technology to redirect proteins towards specific areas of the genome
The Spanish National Cancer Research Centre (CNIO) Macromolecular Crystallography Group has managed to reprogramme the binding of a protein called BuD to DNA in order to redirect it towards specific DNA regions.
16 July 2014
International science team solve biological mystery
An international team of researchers, led by the University of Leicester, has solved a long-standing mystery in biology, by identifying the molecular structure of a vital biological chemical.
15 July 2014
In the gut, immunity is a two-way street
In recent years, it has become clear that many diseases are triggered or maintained by changes in bacterial communities in the gut. The general view has been that bacteria stimulate the immune system, leading to inflammation or autoimmune disorders.
14 July 2014
Scientists identify protein in bacteria with essential role in survival
Scientists have identified a protein that is essential to the survival of E. coli bacteria, and consider the protein a potential new target for antibiotics.