10 March 2014
First animals oxygenated the ocean, study suggests
The evolution of the first animals may have oxygenated the earth’s oceans – contrary to the traditional view that a rise in oxygen triggered their development.
7 March 2014
Drug protects mice against malaria brain damage and raises levels of BDNF in humans
Cerebral malaria is a serious complication of infection with the malaria parasite, affecting approximately one in a thousand children in areas where malaria is common.
6 March 2014
New molecules doom proteins with kiss of death
Newly engineered molecules called ‘ubiquibodies’ can mark specific proteins inside a cell for destruction – a molecular kiss of death that is paving the way for new drug therapies and powerful research tools.
5 March 2014
Alzheimer’s in a dish
Harvard stem cell scientists have successfully converted skins cells from patients with early-onset Alzheimer’s into the types of neurons that are affected by the disease, making it possible to study this leading form of dementia in living human cells.
4 March 2014
New discovery solves problem of anti-inflammatory substance
There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body’s inflammatory response.
3 March 2014
Imaging dynamics of small biomolecules inside live cells
Researchers at Columbia University have made a significant step toward visualizing small biomolecules inside living biological systems with minimum disturbance, a longstanding goal for scientists.
28 February 2014
Huntington proteins and their nasty ‘social network’
A large-scale protein interaction network for Huntington’s disease has increased our knowledge of disease pathology and therapeutic targets.
27 February 2014
Optoswitches turn pain off and sight on
Photoreactive compounds can directly modulate nerve-cell function, opening new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment.
26 February 2014
Brain cell activity regulates Alzheimer’s protein
Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer’s disease, according to new research from scientists at Washington University School of Medicine in St. Louis.
25 February 2014
Mdm2 suppresses tumours by pulling the plug on glycolysis
Cancer cells have long been known to have higher rates of the energy-generating metabolic pathway known as glycolysis.
24 February 2014
Degradation of viral DNA in the cell nucleus is opening up new treatment
Viruses such as HBV can persist by depositing their genetic information (DNA) in the cell nucleus, where the DNA is normally not degraded. This prevents antiviral drugs from eliminating these viruses.
21 February 2014
Roots to Shoots: hormone transport in plants deciphered
Regulating hormone distribution mechanisms in plants could lead to sustainable bioenergy crops with increased growth and reduced needs for fertilizer.
20 February 2014
Molecular aberration signals cancer
Scientists have made a discovery that strongly links a little understood molecule, which is similar to DNA, to cancer and cancer survival.
19 February 2014
Theory on origin of animals challenged: complex life gets by on very little oxygen
One of science’s strongest dogmas is that complex life on Earth could only evolve when oxygen levels in the atmosphere rose to close to modern levels.