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28 November 2014
Classical enzymatic theory revised by including water motions
The main focus of enzymology lies on enzymes themselves, whereas the role of water motions in mediating the biological reaction is often left aside owing to the complex molecular behaviour.


27 November 2014
How muscles work
Scientists led have elucidated the molecular structure and regulation of the essential muscle protein α-actinin.


26 November 2014
A link between DNA transcription and disease-causing expansions
Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich’s ataxia and Huntington’s disease.


25 November 2014
Scientists model dynamic instability of microtubules
New computer models that show how microtubules age are the first to match experimental results and help explain the dynamic processes behind an essential component of every living cell, according to Rice University scientists.


24 November 2014
Extremophiles may be an untapped source of antibacterial drugs
Extremophile microorganisms such as those that live around deep sea hydrothermal vents may be a new, untapped source for antibacterial drugs.


21 November 2014
Of mice, not men
For more than a century, the laboratory mouse (Mus musculus) has stood in for humans in experiments ranging from deciphering disease and brain function to explaining social behaviours and the nature of obesity.


19 November 2014
A bird’s-eye view of the protein universe
How exactly did proteins first come to be? Do they all share a single common ancestor? Or did proteins evolve from many different origins?


18 November 2014
Chlamydia knock out the body's own cancer defence
By breaking down the cancer-suppressing protein p53, Chlamydia prevents programmed cell death and favours the process of cancer development.


17 November 2014
Scientists uncover mechanism that controls the fitness of cells, affecting aging and disease
A novel looping mechanism that involves the end caps of DNA may help explain the aging of cells and how they initiate and transmit disease, according to new research from UT Southwestern Medical Center cell biologists.


14 November 2014
Scientists uncover vast numbers of DNA ‘blind spots’ that may hide cancer-causing mistakes
Cancer Research UK scientists have found more than 400 ‘blind spots’ in DNA which could hide cancer-causing gene faults, according to research published today in Cancer Research.


13 November 2014
HIV virulence depends on where virus inserts itself in host DNA
The human immunodeficiency virus (HIV) can insert itself at different locations in the DNA of its human host – and this specific integration site determines how quickly the disease progresses.


12 November 2014
What algae do in the dark
Photosynthesis enables plants, algae, and select bacteria to transform the energy from sunlight during the daytime into chemical energy and it involves taking in carbon dioxide from the air and releasing oxygen derived from water molecules.


11 November 2014
Thousands of never-before-seen human genome variations uncovered
Thousands of never-before-seen genetic variants in the human genome have been uncovered using a new genome sequencing technology. These discoveries close many human genome mapping gaps that have long resisted sequencing.


10 November 2014
Researchers take new approach to stop ‘most wanted’ cancer protein
Researchers have found a way to defeat one of the most tantalizing yet elusive target proteins in cancer cells – employing a strategy that turns the protein’s own molecular machinations against it.




 
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