18-19 April 2011
Analysis of free radicals, radical modifications and redox signalling
Aston University, Birmingham, UK
A Biochemistry Society Focused Meeting. Poster abstract deadline: 31 January 2011
Abstract submission is now open. Earlybird registration deadline: 18 March 2011.
Registration is now open.
Proceedings (invited speakers) will be published in Biochemical Society Transactions
Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.
Student Travel Grants are available for this meeting.
A Biochemistry Society Linked Focus Meeting Meeting descriptionThe importance of free radicals in biological systems has been recognized for many decades but until recently, was largely viewed as a deleterious aspect of inflammation and toxicity. However, strong evidence has now emerged that many radical modifications to biomolecules are reversible and have a regulatory role. In particular, the susceptibility of proteins for rapid and reversible free radical-mediated alterations in structure and function allows them to act as signalling intermediates that are sensitive to redox environment.
In view of the growing importance of redox signalling in biochemistry and pathology, the development of robust methods for accurate determination of cellular levels of free radicals and oxidants, as well analysis of biomolecule oxidation, is critical in the field. This meeting will focus on state of the art methodology for these areas, and discuss the limitations and pitfalls therein. The aims of the meeting are therefore to provide the participants with an enhanced understanding of (1) the best methods for measuring reactive oxygen species and nitrogen species, (2) modern approaches to detecting specific types of oxidative post-translational modifications, (3) methodology for analysis of lipid oxidation products with relevance to signalling. This focused meeting will be of prime importance to all researchers in the oxidative stress and redox signalling areas.
TopicsFree radicals
Reactive nitrogen species
Oxidative post-translational modifications
Redox signalling
Lipid oxidation products
Imaging
Mass spectrometry
Magnetic resonance techniques
Further information:
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