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28-30 March 2012

LRRK2: function and dysfunction

Royal Holloway, University of London, UK

A Biochemical Society Focused Meeting

Meeting background

Mutations in the multidomain enzyme LRRK2 are the most common genetic cause of Parkinson’s disease, but despite intensive investigation we still know very little about the normal function of this protein or how mutations lead to disease.


  • LRRK2 enzymatic function
  • The structure and function of LRRK2
  • LRRK2 substrates and interacting proteins
  • LRRK2 and cellular dysfunction
  • Will inhibiting LRRK2 be a useful strategy to treat Parkinson’s disease

Reviews by the speakers, based on their presentations at this major international meeting, will be published exclusively in Biochemical Society Transactions (Volume 40, part 5).

Abstract deadline: 1 February 2012.

Online abstract submission is now closed. If you wish to submit an abstract please contact the Conference Office. Late abstracts will not appear in the programme book.

Earlybird registration deadline: 27 February 2012.

Registration for this Conference has now reached capacity. If you would like to be added to the waiting list, please contact the conference office.

The ASN NEURO Poster Prize was awarded to Evy Lobbestael from Katholieke Universiteit Leuven, Belgium for her poster entitled "Identification of protein phosphatase 1 as a regulator of the phosphorylation of LRRK2 in cells".

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Student Bursaries are available for this meeting.

Approved by the Society of Biology for the purpose of CPD, this event may be counted as 54 CPD credits.

'Eureka Moments: making proteins, making a difference'. As part of our centenary celebrations, a number of the Society’s Honorary Members have been asked to talk about the important moments in their careers and the future of the discipline.

The third to be released is that of Greg Winter who spoke to Michael Neuberger and Brian Hartley about the important moments in his career and the future of the discipline. Watch the interview now!

Further information:
Website: http://www.biochemistry.org/Conferences/AllConferences/tabid/379/View/Conference/MeetingNo/SA130/Default.aspx
Email: conferences@biochemistry.org
Telephone: +44 (0) 20 7685 2450

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